My laboratory is focused on studying multiple sclerosis (MS), a debilitating neurodegenerative disease. There is a critical need to broaden our understanding of the mechanisms that contribute to pathology during MS. Current clinical treatments are only able to slow down MS progression, with no cure for this devastating disease. The goal of my laboratory is to explore promising avenues aimed at discovering novel therapeutic options for multiple sclerosis patients. Since I started my laboratory in 2012, I have encouraged my trainees to pursue new projects at the forefront of MS research. My trainees have developed projects centered on understudied aspects of MS pathology with the hope of developing the next generation of MS therapeutics. We study signaling pathways that encompass microbiome function, metabolism regulation, endoplasmic reticulum (ER) function and myelin biology.